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Partial-breast radiotherapy after breast conservation surgery for women with early breast cancer: 10-year outcomes from UK IMPORT LOW

The IMPORT LOW trial evaluated partial-breast radiotherapy with intensity-modulated radiotherapy in women with early-stage breast cancer at below average risk ...
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Pfizer has discontinued the development of Danuglipron, an oral glucagon-like peptide-1 receptor agonist

Pfizer has announced the decision to discontinue development of Danuglipron ( PF-06882961 ), an oral glucagon-like peptide-1 (GLP-1) receptor agonist, ...
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Scemblix based on Asciminib for adults with chronic myeloid leukemia, superior efficacy versus all standard of care therapies. Approved by FDA

Scemblix ( Asciminib ) has received accelerated approval by the US Food and Drug Administration (FDA) for adult patients with ...
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FDA has approved Yescarta for relapsed or refractory follicular lymphoma after two or more lines of systemic therapy

The U.S. Food and Drug Administration ( FDA ) has granted accelerated approval to Yescarta ( Axicabtagene ciloleucel ) for ...
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V920 Ebola Zaire vaccine for protection against Ebola virus disease

The Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMA ) has ...
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PanCancer Atlas: NIH has completed in-depth genomic analysis of 33 cancer types

A detailed genomic analysis, known as the PanCancer Atlas, on a data set of molecular and clinical information from over ...
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Angiotensin receptor blocker-neprilysin inhibitor: pharmacogenomics and long-term side effects

The development of the agent Sacubitril / Valsartan ( Entresto ), known as an angiotensin receptor blocker-neprilysin inhibitor ( ARNI ...
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A link between the gut and heart health

One of the more intriguing recent discoveries has to do with the role of the gut microbiome ( the trillions ...
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Clinical findings on vestibular migraine in children and adolescents

Vestibular migraine ( VM ) is the most common cause of episodic vertigo in children. Researchers have summarized the clinical ...
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Patients with chronic kidney disease: vitamin D, vitamin D receptor and the importance of its activation

Vitamin D deficiency has been linked to many different pathologies, especially with morbidity and mortality in patients with chronic kidney ...
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Severe vitamin D receptor mutations: vitamin D might not be essential for skeletal health in adulthood

Researchers have reported the long-term follow-up of two patients with severe vitamin D receptor mutations, who had normal bone mass ...
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Even mild traumatic brain injury may cause brain damage and thinking and memory problems

Even mild traumatic brain injury may cause brain damage and thinking and memory problems, according to a study published in ...
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Surgery and hybrid procedures for atrial fibrillation

In several retrospective studies analysing whether existing preoperative atrial fibrillation ( AF ) is a risk factor for a poorer ...
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High-sensitivity cardiac troponin assay and the under diagnosis of myocardial infarction in women

High-sensitivity cardiac troponin assays have identified differences in the normal reference range for cardiac troponin between men and women. Current ...
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Cardiac resynchronisation therapy: no benefit, even harm, in narrow QRS heart failure

Cardiac resynchronisation therapy ( CRT ), a standard care for heart failure patients with wide QRS durations, offered no benefit ...
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Patients infected with hepatitis C virus: FDA has approved first genotyping test

The FDA ( Food and Drug Administration ) has approved a test that identifies the genotypeof hepatitis C virus ( ...
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Non-melanoma skin cancer associated with reduced risk for Alzheimer's disease

People who have non-melanoma skin cancer may be less likely to develop Alzheimer's disease, according to research carried out by ...
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Longitudinal deformation of coronary stents: Promus Element

A study has reported clinical experience with longitudinal stent deformation ( LSD ) and observations from the bench. Longitudinal stent deformation ...
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Aortic valve stenosis: Sapien artificial valve approved by FDA for patients eligible for surgery, but at high risk for serious surgical complications or death

The FDA ( Food and Drug Administration ) has expanded the approved indication for the Sapien Transcatheter Heart Valve ( ...
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Disease-modifying antirheumatic drugs: TNF inhibitors and Hydroxychloroquine are associated with a reduced risk for the development of diabetes in psoriasis and rheumatoid arthritis patients

Patients with systemic inflammatory conditions, such as rheumatoid arthritis and psoriasis, experience a 1.5 to 2-fold increased rate of cardiovascular ...
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The patients who are most likely to benefit from CRT-D are those with at least some dyssynchrony who have relatively preserved contractile function

Patients with dyssynchronous yet viable ventricles are most likely to benefit from cardiac resynchronization therapy combined with defibrillation, concludes the ...
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Relationship between multiple sclerosis and chronic cerebral venous insufficiency

A study, conducted by University at Buffalo ( UB ) researchers, published in the Neurology, the journal of the American ...
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FDA clears biomarker test to estimate the risk of ovarian cancer in women with a pelvic mass

The FDA ( Food and Drug Administration ) has granted 510(k) clearance for marketing and use of a combination of ...
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Subclinical thyroid dysfunction linked to hip fractures in older men

New research from University of California ( UC ) Davis Health System has found that older men with subclinical thyroid ...
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ESC Guidelines 2010: acute management of atrial fibrillation

The acute management of patients with atrial fibrillation ( AF ) is driven by acute protection against thrombo-embolic events and ...
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Risk of prostate cancer linked to Chlordecone exposure

Researchers have shown that exposure to Chlordecone ( Kepone ), an organochlorine chemical with well defined estrogenic properties used in ...
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Multiple sclerosis: mindfulness meditation may ease fatigue and depression

Learning mindfulness meditation may help people who have multiple sclerosis with the fatigue, depression and other life challenges that commonly ...
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MRI better than CT scan at diagnosing stroke

Physicians should use a diffusion MRI scan to diagnose stroke instead of a CT ( computerised tomography ) scan, according ...
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Multiple sclerosis: mentally active lifestyle may protect against the memory and learning problems

A new study has shown that a mentally active lifestyle may protect against the memory and learning problems that often ...
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Mutations in VCP gene cause some cases of familial amyotrophic lateral sclerosis

Using a new gene sequencing method, a team of researchers from Johns Hopkins and the National Institutes of Health has ...
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